Ralf P Brandes Selected Research

Proteins (Proteins, Gene)

1/2022	SPARC, a Novel Regulator of Vascular Cell Function in Pulmonary Hypertension.
1/2021	Mapping the Endothelial Cell S-Sulfhydrome Highlights the Crucial Role of Integrin Sulfhydration in Vascular Function.
10/2020	Deletion of NoxO1 limits atherosclerosis development in female mice.
12/2019	The polarity protein Scrib limits atherosclerosis development in mice.
3/2012	Hypoxia induces Kv channel current inhibition by increased NADPH oxidase-derived reactive oxygen species.
10/2011	MicroRNA-29 in aortic dilation: implications for aneurysm formation.
10/2008	Differential vascular functions of Nox family NADPH oxidases.
8/2008	Cellular properties of C-terminal KCNH2 long QT syndrome mutations: description and divergence from clinical phenotypes.
3/2007	Inactivation of extracellular superoxide dismutase contributes to the development of high-volume hypertension.
1/2005	Vascular NADPH oxidases: molecular mechanisms of activation.

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Ralf P Brandes Research Topics

Disease

20	Inflammation (Inflammations) 01/2023 - 07/2003
17	Atherosclerosis 01/2024 - 08/2006
16	Hypoxia (Hypoxemia) 01/2023 - 07/2006
14	Hypertension (High Blood Pressure) 01/2022 - 10/2003
12	Pulmonary Hypertension 11/2022 - 07/2006
7	Vascular Diseases (Vascular Disease) 01/2021 - 10/2008
6	Myocardial Infarction 01/2023 - 03/2006
6	Vascular Remodeling 12/2017 - 09/2005
6	Cardiovascular Diseases (Cardiovascular Disease) 12/2015 - 01/2005
5	Ischemia 04/2013 - 11/2007
4	Fibrosis (Cirrhosis) 12/2023 - 09/2007
4	Neoplasms (Cancer) 03/2022 - 01/2018
4	Emphysema 01/2022 - 06/2014
4	Reperfusion Injury 01/2019 - 09/2010
4	Hypertrophy 03/2015 - 09/2010
3	Neointima 01/2023 - 05/2010
3	Chronic Obstructive Pulmonary Disease (COPD) 01/2023 - 01/2020
3	Body Weight (Weight, Body) 01/2022 - 06/2011
3	Familial Primary Pulmonary Hypertension 01/2022 - 02/2009
3	Neuralgia (Stump Neuralgia) 01/2021 - 07/2012
3	Aneurysm (Aneurysms) 03/2014 - 10/2011
3	Albuminuria 01/2013 - 08/2010
3	Stroke (Strokes) 07/2012 - 11/2007
2	Pain (Aches) 08/2023 - 07/2012
2	Vascular System Injuries 01/2021 - 04/2002
2	Heart Diseases (Heart Disease) 01/2021 - 10/2010
2	Sepsis (Septicemia) 01/2019 - 12/2014
2	Atherosclerotic Plaque (Atheroma) 01/2019 - 10/2008
2	Coronary Artery Disease (Coronary Atherosclerosis) 12/2018 - 02/2003
2	Aortic Aneurysm (Aneurysm, Aortic) 01/2018 - 12/2013
2	Liver Diseases (Liver Disease) 10/2017 - 07/2012
2	Renovascular Hypertension (Goldblatt Syndrome) 06/2014 - 10/2003
2	Ischemic Stroke 04/2013 - 07/2012
2	Cardiomegaly (Heart Hypertrophy) 06/2011 - 08/2006
2	Heart Failure 02/2011 - 06/2006
2	Brain Injuries (Brain Injury) 10/2010 - 11/2007
2	Hyperlipidemias (Hyperlipidemia) 10/2008 - 11/2006
1	Mental Disorders (Mental Disorder) 08/2023
1	Chronic Pain 08/2023
1	Arteriovenous Malformations (Arteriovenous Malformation) 01/2023
1	Pneumonia (Pneumonitis) 01/2023
1	Arteriosclerosis 01/2023

Drug/Important Bio-Agent (IBA)

25	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 04/2002
24	NADPH Oxidases (NAD(P)H oxidase)IBA 10/2020 - 04/2003
10	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2005
8	Angiotensin IIIBA 12/2013 - 10/2003
7	Tamoxifen FDA LinkGeneric 01/2022 - 04/2012
7	EnzymesIBA 01/2022 - 07/2003
7	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2020 - 01/2005
7	Epoxide HydrolasesIBA 01/2019 - 04/2005
6	AntioxidantsIBA 01/2023 - 10/2010
6	Superoxides (Superoxide)IBA 01/2020 - 07/2004
6	MonocrotalineIBA 07/2017 - 02/2009
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 08/2014 - 02/2003
4	Oxygen (Dioxygen)IBA 11/2022 - 01/2005
4	SmokeIBA 01/2022 - 01/2008
4	NADPH Oxidase 4IBA 01/2021 - 10/2017
4	LipidsIBA 01/2019 - 12/2004
3	Transcription Factors (Transcription Factor)IBA 03/2022 - 03/2016
3	Hormones (Hormone)IBA 01/2021 - 09/2014
3	ApolipoproteinsIBA 01/2019 - 12/2013
3	CytokinesIBA 01/2018 - 01/2008
3	Messenger RNA (mRNA)IBA 12/2014 - 04/2002
3	Oxidoreductases (Dehydrogenase)IBA 03/2014 - 11/2007
3	Protein Isoforms (Isoforms)IBA 04/2013 - 02/2012
3	NADP (NADPH)IBA 07/2012 - 03/2006
2	RNA (Ribonucleic Acid)IBA 12/2023 - 01/2021
2	Hypoxia-Inducible Factor 1IBA 03/2022 - 09/2014
2	Cysteine (L-Cysteine)FDA Link 01/2022 - 08/2017
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2022 - 01/2020
2	NitratesIBA 01/2021 - 08/2008
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2021 - 08/2017
2	Nitroglycerin (Dynamite)FDA LinkGeneric 01/2021 - 08/2008
2	LyasesIBA 01/2020 - 01/2019
2	CystathionineIBA 01/2020 - 01/2019
2	Long Noncoding RNAIBA 01/2020 - 01/2019
2	Toll-Like Receptor 4IBA 01/2019 - 10/2017
2	BiglycanIBA 01/2019 - 01/2016
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2018 - 03/2014
2	Sulfhydryl Compounds (Thiols)IBA 12/2017 - 08/2014
2	LipopolysaccharidesIBA 10/2017 - 07/2013
2	CalciumIBA 08/2017 - 10/2011
2	rho-Associated KinasesIBA 06/2014 - 01/2013
2	Diltiazem (Cardizem)FDA LinkGeneric 03/2014 - 12/2013
2	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 12/2013 - 04/2005
2	Ramipril (Altace)FDA LinkGeneric 01/2013 - 08/2010
2	Endothelin-1 (Endothelin 1)IBA 06/2011 - 12/2004
2	Apolipoproteins E (ApoE)IBA 05/2010 - 11/2006
2	Acetylcholine (Acetylcholine Chloride)FDA Link 11/2006 - 07/2006
2	Endothelins (Endothelin)IBA 06/2006 - 12/2004
1	CholesterolIBA 01/2024
1	AcetylesteraseIBA 12/2023
1	Pheniramine (Pheniramine Maleate)FDA Link 08/2023
1	SphingolipidsIBA 08/2023
1	LectinsIBA 08/2023
1	Propranolol (Inderal)FDA LinkGeneric 01/2023

Therapy/Procedure

10	Ligation 12/2019 - 10/2008
6	Therapeutics 01/2021 - 07/2012
2	Punctures 01/2019 - 12/2014
2	Nephrectomy 01/2013 - 08/2012